Fatigue as a culprit in blunt-end info/knowledge sharing failure

I just came back from a great trip -- which resulted in jet lag. Yep - I am fatigued. It makes me wonder about the lack of discussion around understanding how blunt end fatigue can result in problems in safety due to ineffective or unreliable information and knowledge delivery. Granted, it would have a different impact on care processes, but could this be a "latent" failure? For example, the recent discussion about the Scottish health authority inaction on adverse clinical event reports. Could that be related to blunt end staff burnout and fatigue? How many of us in either safety or the information/knowledge fields work weekends and long hours to keep their projects progressing smoothly? Can that extra effort contribute to factors that could contribute to information failures?